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It is the standard diluent for reconstituting lyophilized peptide and small-molecule research compounds at the bench

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For instance, zopolrestat (1 μM) attenuated ischemia-reperfusion injury in isolated diabetic rat hearts by reducing sorbitol and fructose accumulation, preserving ATP, and restoring redox balance [148], while results from a separate study revealed that it also normalized lactate and glutamate production, corrected the elevated NADH/NAD + ratio, and shifted substrate utilization from fatty acid oxidation (FAO) toward glycolysis [149]