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For example, mucroporin-M1 induced destruction of the viral envelope [17], whereas targeting the heptad repeat 2 (HR2)-M2, EK1, EK1C4, and TMPRSS2 within the viral Spike (S) protein to inhibit protein-mediated fusion, the S2 subunit HR1 domain, and S-protein priming processes, respectively [18–20]

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Activity in old mice macrophages was not influenced in a statistically important manner [47,48]