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Pharmacokinetic Analysis Pharmacokinetic analysis was performed using data from individual rats from which the mean and standard error of the mean (SEM) were calculated for each group

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3.4 Changes in serum homocysteine by supplementation route and dosage Analysis of 10 comparisons showed that vitamin B12 supplementation was associated with a mean reduction of −35.8% in serum homocysteine concentrations (Supplementary Table S5)