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As the CPZ + rapamycin in vivo model is reported to produce significant myelin loss at 4 weeks of treatment, it is possible that a longer exposure of slices to CPZ + rapamycin could induce the same effect (Sachs et al., 2014)

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[DOI] [PubMed] [Google Scholar] 79.de Stefano D., Maiuri M.C., Simeon V., Grassia G., Soscia A., Cinelli M.P., Carnuccio R