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[326] Some commenters suggested that CMS remove the once-per-lifetime use of MDPP at § 410.79(f), while other commenters advocated for making MDPP a permanent Medicare benefit to provide long-term stability and encourage continued beneficiary and supplier participation

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Key highlights Tirzepatide (also known by FDA-approved brand names Mounjaro and Zepbound) is a dual receptor agonist (GLP-1/GIP) that helps reduce appetite, control blood sugar, and promote greater weight loss than single receptor GLP-1 receptor agonists, such as semaglutide