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Scorpio undergoes multiple preparatory methods—such as boiling (in plain water or saltwater), mint processing, licorice rinsing, and alcohol rinsing—prior to clinical application, aimed at mitigating toxicity while preserving pharmacological activity (Zhang et al., 2024)
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Compared to ulcerative colitis, in which the AMP system seems to be adequately induced, colonic Crohn's disease is characterized by low HBD1, regulated by peroxisome proliferator-activated receptor gamma (PPARγ), and a compromised induction of HBD2 and HBD3 (307, 308)
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