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IFN-γ is responsible for macrophage activation, enhanced antigen presentation, and induction of nitric oxide-mediated killing mechanisms ( Our preclinical studies confirmed the previous findings that the T2DM group has lower levels of IFN-γ ( Figure 3E ) and TNF-α ( Figure 3F ) when compared to healthy individuals
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These antioxidants have been demonstrated to prevent or slow the progression of cataracts in vitro, ex vivo and in vivo (31,106,116,130,143,144)