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Further support for these findings comes from transcriptome and gene array analyses of liver tissue from dogs with hepatitis and age-related hepatic changes, which suggest the enhanced expression of genes related to OS and inflammation in hepatic dysfunction [95,99]
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4.3 Shigella flexneri Shigella employs a type III secretion system to induce uptake of the bacterium into a vacuole, which is then lysed, and bacterial replication occurs within the host cytoplasm (Pieper et al., 2013)