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Moreover, activated nitro-oxidative stress pathways in PD may also cause comorbid depression, characterized by activated immune and nitro-oxidative stress pathways [171]
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In addition, widely studied experimental NRF2 inducers encompass natural and synthetic compounds such as sulforaphane (SFN) (Ma et al., 2023), bardoxolone methyl (CDDO-Me) (Abed et al., 2015), and curcumin (Patel et al., 2020)
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