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For example, dasatinib and quercetin reduce SASP cytokines by promoting apoptosis of ROS-rich senescent cells, while fisetin decreases oxidative stress burden and downregulates NF-κB signaling, thereby dampening SASP output

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Ibotenate is a compound that occurs in the mushrooms Amanita muscaria and Amanita pantherina (83), while quisqualate naturally occurs in the seeds of the vine Quisqualis indica