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Further studies have shown that the combination of cisplatin and the ferroptosis inducer erastin enhances the antitumor effect of drugs, indicating that ferroptosis has great potential in antitumor therapy, thus opening a new manner for the in-depth application of classical drugs 44
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Disruption of mitochondrial function, ATP synthesis, and mitochondrial gene expression profile have been observed as side effects of AFs in the animal and human bodies (276)
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