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Option:12 Packs (180 ct)
When PUMA is translocated into the cytoplasm it disrupts the Bcl-X L /p53 complex and liberates p53 (Chipuk et al., Bax induces permeabilization of the outer mitochondrial membrane to trigger cell death through the release of cytochrome c from the mitochondria (Marzo et al., 1998
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