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9,22 The ligand can target and bind to particular receptors overexpressed on diseased cell surfaces, with little off-target effects to healthy cells

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One research team constructed novel NPs comprising self-assembling peptides for rapid anti-inflammatory programming (SPRAY), which self-assemble to form NPs, by screening to identify the best SPRAY candidate, namely, the peptide BLKR (Figure 4) (Jing et al., 2015)