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Vitamin B12 is essential to the creation and regeneration of red blood cells, also known as hemoglobin, which transport oxygen and nutrients throughout your body to other cells
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In the absence of vitamin B 12 (Co(I)-Cbl), dietary 5-MTHF cannot enter the folate cycle and is not polyglutaminated, and cannot accumulate inside the cell, with the result that the levels of available intracellular folate are reduced
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