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While the PP2A/AKT axis has not been examined in astrocytes, β -arrestin-mediated recruitment of PP2A is a major mechanism by which D2-like receptors inhibit Akt (Beaulieu et al., 2005, 2015
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We discuss the importance of intrinsic β-cell metabolic oscillations, the phasic alignment of relevant metabolic cycles, shuttles and shunts, and how their temporal and compartmental relationships align with the triggering phase or the secretory phase of pulsatile insulin secretion