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The failure of Ca 2+ -ATPase could be a natural process of aging or pathological conditions [248]
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MASLD serves as an umbrella term that encompasses a broad spectrum of pathological liver changes – from simple hepatic steatosis to steatohepatitis associated with metabolic dysfunction, which can lead to fibrosis and eventually progress to cirrhosis or hepatocellular carcinoma (HCC), while simultaneously increasing the risk of cardiovascular diseases (CVDs) and extrahepatic malignancies [1]
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