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Another connection occurs with neuropathy, a type of nerve damage that’s associated with multiple conditions and causes unpleasant and even life-altering symptoms, including burning, tingling, and pain
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GSH is synthesized by two sequential ATP-requiring enzymes, namely the γ-glutamyl-cysteine (γ-GC) synthetase (γ-GCS, EC 6.3.2.2), which forms γ-GC from L-glutamic acid and L-cysteine, and the GSH synthetase (GS, EC 6.3.2.3), which forms GSH from γ-GC and L-glycine, as shown in Figure 4