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In addition, another IBO provided analytical data on five batches of sodium saccharin (E 954 (ii)) in which the purity ranged from 99.82% to 100.07%, and on the levels of potential impurities, such as 1,2‐benzisotiazoline‐3‐one, methyl benzoate, methyl anthranilate, phthalates and their derivatives, benzamide, 2‐chlorobenzamide, N‐methyl saccharin, 2‐chlorobenzene sulfonamide and dibutyl phthalate (all below the LOD of 0.1 mg/kg in all batches) (Documentation provided to EFSA n
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PTS also decreased the level of MDA, increased the level of SOD, GSH, and the expression of Trx-1 in DOX-treated mice
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