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Salivary samples collected from the OXT treatment group at baseline, end of treatment period, four weeks after, and one year after, found that endogenous OXT levels remained higher 4 weeks post-treatment, indicating that repeated IN-OXT administration can induce long-lasting changes in endogenous OXT levels, likely through a self-perpetuating feedforward elevation of OXT correlated with the positive effects of OXT on social behaviors [157]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Kim J, et al