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[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Brookes MJ, Liddle EB, Hale JR, Woolrich MW, Luckhoo H, Liddle PF, et al

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The α-MSH trigger signal activates ERK after phosphorylation of MEK by cAMP, and p-ERK promotes MITF degradation and inhibits melanin production (Shirasugi et al., 2010

ageing causes a decline in the production of cell energy