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Broadly speaking, inflammatory macrophages increase production of proinflammatory cytokines IL-6, TNFα, IL-1β, and type I interferons that create a harmful feedforward immune cell recruitment-activation cycle 2,74,104,105
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Researchers hypothesized that a gastric peptide factor might be involved in maintaining bone health, which partly explains the rationale for studying BPC-157 in bone healing contexts
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