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5.2 Clinical trials of interventions targeting endogenous antioxidant defenses Enhancing endogenous antioxidant defenses, particularly the GSH system, is another strategy to combat ferroptosis

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sativa seedlings demonstrated high flood tolerance, reduced oxidative injury and fast plant growth rates (Chiang et al., S -nitrosylation of Arabidopsis APX1 at Cys32 increased the H 2 O 2 scavenging activity of enzyme, resulting in improved oxidative stress tolerance (Yang et al., 2015)