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Frontiers | Development of roGFP2-derived redox probes for measurement of the glutathione redox potential in the cytosol of severely glutathione-deficient rml1 seedlings
While these preclinical findings are promising, a phase I-II clinical trial of HSV-1 TK therapy in patients with recurrent GBM showed only marginal clinical benefit [87], questioning the applicability of this approach
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