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Brief Narrative Review of Peyronie’s Disease Treatment with Antioxidants Although a number of guidelines contain no recommendation for the use of antioxidants in the treatment of PD, they have been used in several therapeutic experiences, either alone or in combination with other substances [168,169]

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Finally, the positive effects of glucocorticoids are recently highlighted in a study where glucocorticoids, via GR regulation of krüppel like factor (KLF)-13 [86], a zinc finger transcription factor involved in cardiac development, protect cardiomyocytes from DNA damage and cell death induced by cobalt(II) chloride hexahydrate (CoCl 2 ·6H 2 O) and the antineoplastic drug doxorubicin [87]