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Another member of the ABC family in wheat known as LR34, controls durable disease resistance against some of the most devastating fungal pathogens such as leaf rust and stripe rust, potentially by exporting other antifungal metabolites although the mechanism is currently not understood ( TRANSPORT MEDIATED BY VESICLE TRAFFICKING IN PLANT CELLS Along with the classical transport of metabolites, emerging evidence suggests the participation of a membrane vesicle-mediated trafficking of metabolites (Petrussa et al., 2013)
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For optimal results, patients are advised to apply the cream twice daily to the affected area, massaging it in until it is fully absorbed