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PROTOCOL OF A PHASE II RANDOMIZED, MULTI-CENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF S-ADENOSYL METHIONINE IN PARTICIPANTS WITH MILD COGNITIVE IMPAIRMENT OR DEMENTIA DUE TO ALZHEIMER'S DISEASE • The Journal of Prevention of Alzheimer's

Glia 56 , 378–386 (2008)

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An increase in relative fluorescence, corresponding to protein thermal unfolding, was determined over a temperature range of 20 °C to 80 °C in increments of 0.5 °C for 10 s