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In addition to affects on cell elongation and disruption of cellular junctions, interaction of CagA and Par1b also causes spindle dysfunction, which delays progression from prophase to metaphase and is hypothesized to result in DNA instability (Lu et al., 2009)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 239.Wang J., Guo Y., Lu W., Liu X., Zhang J., Sun J., Chai G