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ADE is induced when the stoichiometry is below the threshold for neutralization
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PMC What to expect at 8 weeks: More noticeable brightening of dull or uneven areas Reduction in pigment spots, sun spots, or mild freckles Skin tone looks more even, with softer transitions between light/dark zones Better radiance, not just lightness Complementary skincare results (like from sunscreen, vitamins) become more evident However, results still differ widely between people