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When co-cultured with macrophages, OCSCs increase the expression of M2-associated markers such as the mannose receptor (MR), interleukin-10 (IL-10), and arginase-1 (Arg-1), while simultaneously reducing the expression of M1 markers like tumor necrosis factor-α (TNF-α), inducible nitric oxide synthase (iNOS), and CD86
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OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program
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