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86 Notch signaling pathway Notch signaling, intimately involved in embryonic development and maintenance of multicellular organisms in adults, is activated by ligand-receptor interaction between adjacent cells, which leads to successive proteolytic cleavages and releases the notch intracellular domain (NICD)
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[DOI] [PubMed] [Google Scholar] 242.Carey JW, Pinarci EY, Penugonda S, Karacal H, Ercal N
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