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When β -Arr was added back to the purified fractions of β ARK, increased functional desensitization by β ARK was observed (Benovic et al., 1987a)
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For example, several studies support a causal relationship between augmented NNMT activity in cancer cells and tumor proliferation/progression in a variety of cancerous states with potential implications for NNMT as a biomarker for cancer prognosis and a relevant target for anti-cancer therapeutic development
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