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Another study demonstrated that 2 weeks of 20 Hz rTMS enhanced auditory comprehension in AD patients, with treatment effects lasting up to 8 weeks (Zhang et al., 2019)
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Unlike the kinases for which multiple inhibitors have been developed and tested in clinical trials, the most common palmitoylation inhibitor, 2-BP, cannot be used clinically because of its significant off-target activity and toxicity, including inhibition of mitochondrial fatty acid oxidation (247, 248)
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