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Considering the different activation kinetics, for comparison of all four receptors, we focused on the 5 min time point for the phosphorylation of IRS-1, Gab-1 and ERK1/2, and the 15 min time point for Shc, Akt, p70S6K1 and S6 phosphorylation

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10.1016/j.cmet.2006.05.011 180 VoordeJ