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Isotretinoin Treatment for Acne Vulgaris: A Five-Year Retrospective Analysis of Clinical and Biochemical Adverse Effects - PMC
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Treatment of fibroblasts from COPD patients with hemin to activate HO-1 results in reduced cellular senescence, improved mitochondrial function, and reduced ROS production [122] Since Nrf2 activates many other antioxidant genes in addition to HO-1, this suggests that activators of Nrf2 and inhibitors of Keap1 might be even more effective against oxidative stress in COPD