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subsequently, they selectively silence pro-inflammatory cytokine expression (TNF- α , IL-1β, IL-6) and fibrogenic molecular pathways (TGF-β1, Col1a1)
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A part of the liver was fixed in 10% formalin for histopathological examination, while another part was used for determination of MDA and GSH levels, β-catenin and GSK3β levels by enzyme-linked immunosorbent assay (ELISA), FZD-7 receptor and LRP5/6 coreceptors by western blot, cyclin D1, c-Myc, and MDR1 expression levels by qRT-PCR
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