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Declaration of Conflicting Interests The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article

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Extrinsic pathway The extrinsic pathway is primarily initiated by the interaction between cell death ligands and their receptors, leading to the formation of a death-inducing signaling complex (DISC), which subsequently activates caspase-8 and caspase-10 to trigger apoptosis [47]