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Enzymatic defects in pyruvate kinase that have been characterized include thermal lability, increased K m for PEP, and decreased activation by Fru-1,6-BP

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[DOI] [PMC free article] [PubMed] [Google Scholar] 199.Sturgeon J.P., Tome J., Dumbura C., Majo F.D., Ngosa D., Mutasa K., Zyambo K., Besa E., Chandwe K., Kapoma C., et al