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Detailed records support protocol optimization and contribute to the broader research community's understanding of epithalon applications
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Biosignaling molecules closely associated with HO-1 expression and function include both its upstream signals [e.g., Nrf2 (nuclear factor erythroid 2-related factor 2), MAPK, STAT3] and its downstream signals [e.g., peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1), estrogen-related receptor, and hypoxia-inducible factor-1 (HIF-1)]
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