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7,8 In our previous studies, we found that Clopidogrel inhibits human gastric mucosal epithelial cell line GES-1 proliferation then further disrupt the tight junction structure (TJs) of gastric epithelium, 9 through activation of endoplasmic reticulum (ER) stress-induced apoptosis via MKP-5 -mediated p38/MAPK phosphorylation

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