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An 8-year follow-up study of 11,737 middle-aged and older adults in the ELSA-Brasil cohort found a link between sticking more closely to the PHD and reduced cognitive decline ( P = 0.009) [65]

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Pharmacovigilance research on compounded GLP-1 receptor agonists further illustrates how nonstandard products can complicate adverse-event and medication-error reporting [34]