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Helicobacter pylori Virulence Factors The virulence factors of HP are attributed to three pathological mechanisms that maintain the infected status in the GHCs, including colonization (participated in urease, adhesin, and flagellum chemotactic system), immune escape [i.e., lipopolysaccharides (LPS), flagellum, CagA, and VacA], and disease induction (VacA, BabA, and DupA
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