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Recently, researchers characterized a translocation involving histone demethylase KDM5A that resulted in fusion of the H3K4me3-binding PHD finger of KDM5A to the transcriptional activator NUP98, a common leukemia translocation partner, in an acute myeloid leukemia patient (Islam et al
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Concerning the brain, it forms 2% of total body weight with high levels of fatty acids, uses 20% of total body oxygen, and has lower antioxidant activity than other tissues
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