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In the next step rac-(2E)-3-(1 ,3-benzodioxol-5-yl)-N- phenyl-N-(tetrahydro-3-furanyl)-2-propenamide was separated by preparative chiral HPLC into (+)-(2E)- 3-(1 ,3-Benzodioxol-5-yl)-N-phenyl-N-(tetrahydro-3-furanyl)-2-propenamide (99.2%ee) and (-)-(2E)-3- (1 ,3-Benzodioxol-5-yl)-N-phenyl-N-(tetrahydro-3-furanyl)-2-propenamide (100%ee)

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doi: 10.3969/j.issn.1009-0126.2020.09.030 98 YangC.ZhouX.XueY.LiD.WangL.ZhongT.et al